Games like SpaceChem on Steam
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Cogs
Cogs is a puzzle game where players build machines from sliding tiles. Players can choose from 50 levels and 3 gameplay modes. New puzzles are unlocked by building contraptions quickly and efficiently. Inventor Mode: Starting with simple puzzles, players are introduced to the widgets that are used to build machines gears, pipes,...
while True: learn()
You’re a machine learning specialist who makes neural networks but your cat seems to be better at it. Now you must solve puzzles to build a cat-to-human translation system (who knows what else this cat is capable of!). Earn a fortune, buy kickass cat outfits, learn how machine learning really works!
Lightmatter
A first-person puzzler where shadows kill you. Watch your step or be swallowed by the darkness.
World of Goo
World of Goo is a multiple award winning physics based puzzle / construction game made entirely by two guys.
LIT: Bend the Light
Light, darkness and remarkable puzzles! Bend the light to your will in this award winning physics-based puzzle game. Feel like a renaissance engineer, build your own solutions to light puzzles, feel your brain grow and all of that within the beautiful and mysterious world of LIT.
Felix The Reaper
Felix The Reaper is a challenging and strict 3D puzzle game about bringing humans into deadly situations. You are Felix, the ever-dancing bringer of death, who just so happens to be dangerously in love with Life.
Hexcells Infinite
Hexcells Infinite is an ambient logic puzzle game for PC, Mac and Linux.
Automachef
Welcome to Automachef, a resource management puzzler where you design kitchens, program machinery and watch your genius come to life! It’s time to engineer tomorrow’s kitchen, today!
SquareCells
SquareCells is an ambient logic puzzle game.
Electronic Super Joy 2
Electronic Super Joy 2 is a brutally hard platformer, set in a world of brain-smashing electronic music. Run, jump, smash, & slice your way through 55+ weird & different levels, with giant monsters, swarming missiles & secret areas.
Cosmoteer: Starship Architect & Commander
Design and simulate the starships of your dreams! Command your ship or fleet in epic battles and manage your crew while exploring a dangerous galaxy. Play alone or with friends, test your ships in online PvP, and let your imagination reach for the stars!
KAMI
KAMI is deceptively simple: fold out coloured paper to fill the screen in as few moves as possible. Relaxing and easy to pick up, you'll soon find yourself deep in contemplation to perfect each puzzle. Created by State of Play, famous for their handcrafted aesthetic, KAMI has been created with real paper in an elegant Japanese theme.
Disoriented
A first-person puzzle game. Simply walk to the door.
Splice
Splice is an experimental and artistic puzzler. Immerse yourself in its microbial world and start splicing! Every level ("strand") consists of a number of cells that you will need to rearrange into a target structure in several moves ("splices").
The Farmer Was Replaced
Program and optimize a drone to automate a farm and watch it do the work for you. Collect resources to unlock better technology and become the most efficient farmer in the world. Improve your problem solving and coding skills.
And Yet It Moves
And Yet It Moves is a puzzle-platformer, set in a unique world, made of ripped paper. Within the paper-collage you can jump, run and last but certainly not least: rotate the world. Learn how to apply the physical consequences of rotation to master the many tricky situations you may encounter.
