Chromosome Evil on Steam - User reviews, Price & Information

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Dive deep into this Lovecraft-inspired RTS survival. Assemble your team using different classes, skills, and weaponry. It's up to your squad to survive the onslaught of nightmares that are surely coming your way. Will you find the source of the darkness?

Chromosome Evil is a war, atmospheric and singleplayer game developed and published by S.C. 16 BIT NIGHTS S.R.L..
Released on March 24th 2022 is available only on Windows in 2 languages: English and Russian.

It has received 321 reviews of which 273 were positive and 48 were negative resulting in a rating of 7.9 out of 10. 😊

The game is currently priced at 12.49€ on Steam.


The Steam community has classified Chromosome Evil into these genres:

Media & Screenshots

Get an in-depth look at Chromosome Evil through various videos and screenshots.

System requirements

These are the minimum specifications needed to play the game. For the best experience, we recommend that you verify them.

Windows
  • OS *: Windows XP or higher
  • Processor: Pentium 4
  • Memory: 1 GB RAM
  • Graphics: Any
  • DirectX: Version 10
  • Storage: 500 MB available space
  • Sound Card: Any

User reviews & Ratings

Explore reviews from Steam users sharing their experiences and what they love about the game.

Jan. 2026
Chromosome Evil is a dark, uncompromising blend of real-time squad tactics and survival horror that places tension and consequence at the center of its design. Developed and published by S.C. 16 BIT NIGHTS S.R.L., the game deliberately distances itself from conventional real-time strategy formulas, instead focusing on small-scale engagements, limited resources, and a suffocating atmosphere shaped by eldritch horror influences. From the very beginning, it communicates that survival is fragile and that every decision, from squad composition to movement across the map, carries weight. The setting is steeped in cosmic dread rather than straightforward apocalyptic collapse. An ancient, malevolent force has awakened, warping the land and transforming both the dead and the living into grotesque entities. This narrative framework gives the game its oppressive tone, where the enemy is not just numerous but fundamentally alien. The story unfolds more through implication and environment than exposition, allowing the player to piece together the scale of the catastrophe through exploration, encounters, and the slow realization that humanity is vastly outmatched by what it has unleashed. Gameplay revolves around managing a small squad of survivors tasked with venturing into hostile zones to gather supplies, uncover information, and push back against overwhelming threats. Before each mission, players must prepare carefully, selecting personnel, weapons, and limited equipment. Once deployed, the game shifts into real-time tactical control, where positioning, timing, and role specialization are critical. Soldiers serve as frontline combatants, engineers construct defensive structures such as turrets and barricades, and medics are essential for keeping the squad operational during drawn-out engagements. Losing a single member can drastically alter the balance of a mission, reinforcing the sense of vulnerability that defines the experience. One of the game’s strongest elements is how it forces players to constantly weigh risk against reward. Staying longer in a zone may yield valuable resources, but it also escalates enemy pressure, eventually triggering relentless waves that can overwhelm even well-prepared squads. Retreating early preserves lives and supplies but may slow long-term progress. There are no safe choices, only calculated ones, and this constant tension is what gives the game its identity. Ammunition, fuel, and medical supplies are always scarce, and careless spending early on can lead to catastrophic consequences later. Progression is gradual and earned through survival rather than conquest. As the campaign advances, squads can expand in size, gain access to better equipment, and develop specialized skills that improve efficiency and survivability. Early missions often feel brutal and unforgiving, but this difficulty curve is intentional, teaching players to respect enemy behavior, terrain, and the importance of preparation. Over time, mastery emerges not from overpowering foes, but from learning when to fight, when to fortify, and when to flee. Visually, Chromosome Evil embraces a retro pixel-art aesthetic that complements its bleak tone. The top-down perspective keeps encounters readable while maintaining a sense of claustrophobia, as narrow passages and limited sightlines heighten tension. Environments are sparse and decayed, reinforcing the feeling of a world consumed by something far beyond human understanding. Sound design plays an equally important role, using ambient noise and sudden audio cues to create unease and signal imminent danger without relying on overt jump scares. The game’s difficulty and systems are unapologetically demanding, which can be intimidating for newcomers. There is little hand-holding, and early failures are common as players learn the mechanics and rhythm of survival. However, this harshness is also what makes success feel meaningful. Each completed mission and each squad saved from annihilation carries a sense of genuine accomplishment that more forgiving strategy games often lack. Ultimately, Chromosome Evil is a focused and atmospheric tactical survival experience that rewards patience, planning, and respect for its hostile world. It is not designed for players seeking fast-paced action or large-scale battles, but for those who enjoy emergent strategy, oppressive horror themes, and the constant pressure of survival under impossible odds. Within its niche, it stands out as a grim, methodical journey where every victory is hard-won and every mistake is costly, leaving a lasting impression through its blend of strategy and dread. Rating: 8/10
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Dec. 2025
Weapons free in the chemical plant results in instant game over.
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July 2025
If the game had a pause feature to send commands id probably had kept this game but its too much micromanagement for me without it
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March 2025
Very fun little squad-based real time tactics game. Very hard. Multiple endings and routes. Make sure you play with the extra weapons or whatever it is called enabled on launch.
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March 2025
good game from amazing developers. works well on steam deck. score 8,5/10
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Frequently Asked Questions

Chromosome Evil is currently priced at 12.49€ on Steam.

Chromosome Evil is currently not on sale. You can purchase it for 12.49€ on Steam.

Chromosome Evil received 273 positive votes out of a total of 321 achieving a rating of 7.89.
😊

Chromosome Evil was developed and published by S.C. 16 BIT NIGHTS S.R.L..

Chromosome Evil is playable and fully supported on Windows.

Chromosome Evil is not playable on MacOS.

Chromosome Evil is not playable on Linux.

Chromosome Evil is a single-player game.

There are 4 DLCs available for Chromosome Evil. Explore additional content available for Chromosome Evil on Steam.

Chromosome Evil does not support mods via Steam Workshop.

Chromosome Evil does not support Steam Remote Play.

Chromosome Evil is enabled for Steam Family Sharing. This means you can share the game with authorized users from your Steam Library, allowing them to play it on their own accounts. For more details on how the feature works, you can read the original Steam Family Sharing announcement or visit the Steam Family Sharing user guide and FAQ page.

You can find solutions or submit a support ticket by visiting the Steam Support page for Chromosome Evil.

Data sources

The information presented on this page is sourced from reliable APIs to ensure accuracy and relevance. We utilize the Steam API to gather data on game details, including titles, descriptions, prices, and user reviews. This allows us to provide you with the most up-to-date information directly from the Steam platform.

Additionally, we incorporate data from the SteamSpy API, which offers insights into game sales and player statistics. This helps us present a comprehensive view of each game's popularity and performance within the gaming community.

Last Updates
Steam data 27 January 2026 14:20
SteamSpy data 26 January 2026 16:24
Steam price 28 January 2026 20:28
Steam reviews 26 January 2026 19:51

If you'd like to dive deeper into the details about Chromosome Evil, we invite you to check out a few dedicated websites that offer extensive information and insights. These platforms provide valuable data, analysis, and user-generated reports to enhance your understanding of the game and its performance.

  • SteamDB - A comprehensive database of everything on Steam about Chromosome Evil
  • SteamCharts - Analysis of Chromosome Evil concurrent players on Steam
  • ProtonDB - Crowdsourced reports on Linux and Steam Deck Chromosome Evil compatibility
Chromosome Evil
Rating
7.9
273
48
Game modes
Features
Online players
0
Developer
S.C. 16 BIT NIGHTS S.R.L.
Publisher
S.C. 16 BIT NIGHTS S.R.L.
Release 24 Mar 2022
Platforms