Games like Big Pharma on Steam
For those who prefer not to search, lists of the most played, top deals and best free games like Big Pharma are available at the bottom of the page.
Tower Factory
Tower Factory is a tower defense and automation game with roguelite elements. Optimize resource production using conveyor systems while defending against monster waves. Can you find and destroy the enemy tower before it's too late?TerraScape
Build gorgeous kingdoms on floating islands by strategically placing buildings in this cozy City-Puzzler. Discover secret combinations, take on weekly challenges and explore randomly generated maps in various single- and multiplayer game modes.Sunset Routes
Sunset Routes is an easy and intriguing roguelite game. You can choose your crew, put them in the cabins, select your destination, and set sail. Through a series of choices, you can earn profits during the emergency period of the New World and even decide its fate—unintentionally or on purpose.Zombie Cure Lab
Construct a laboratory base full of machinery to cure zombies. Assign workers to gather and process resources, building up your economy. Defend against zombie attacks and convert them into your workforce. Research technologies to develop the final antidote and restore humanity.Luck be a Landlord
Luck be a Landlord is a roguelike deckbuilder about using a slot machine to earn rent money and defeat capitalism. This game does not contain any real-world currency gambling or microtransactions.Siege Survival: Gloria Victis
A medieval city under siege and a handful of civilians are all that keep the walls from falling. Mixing survival strategy and resource management, build your camp, craft supplies, and scavenge the occupied city to supply the last troops holding back the invaders.Freshly Frosted
Place conveyor belts to solve puzzles in the world's most adorable donut factory!Plutocracy
The business simulator Plutocracy gives you the chance to become wealthy and powerful to take control over the world. Where policy, laws, officials and people are only the chess pieces how do you play your game?Jurassic World Evolution
Place yourself at the heart of the Jurassic franchise and build your own Jurassic World. Bioengineer dinosaurs that think, feel and react intelligently to the world around them and face threats posed by espionage, breakouts and devastating tropical storms in an uncertain world where life always finds a way.Xenonauts
Xenonauts is a strategy game in which you control a multi-national military organisation defending a Cold War-era Earth from alien invasion, using small squads of persistent soldiers to eliminate the extraterrestrials and recover their technology in turn-based ground combat.Internet Cafe & Supermarket Simulator 2024
"Internet Cafe & Supermarket Simulator 2024" is a comprehensive simulation game that combines the management of both an internet cafe and a supermarket. Step into the role of a shop owner, apply your business acumen, and expand your empire step by step.Supermarket Together
The multiplayer supermarket has arrived to your neighbourhood for free! Stock your shop space, unlock perks and franchises, hire employees or chase those pesky shoplifters. The more players, the more action!Supermarket Simulator
Run your own supermarket. Stock shelves, set prices as you'd like, take payments, hire staff, expand and design your store. Online orders & delivery, shoplifters, security, local market are upcoming.Pumping Simulator 2
A gas station management game, start by selling a car to raise funds and invest in an abandoned plot of land. Build, expand, and upgrade your gas station, diversify services, customize and manage time efficiently during peak hours. And maybe you will become richSettlements Rising
Settlements Rising is a medieval city building and colony management game. It offers a lively colony experience with simulated villagers, dozens of professions and resources, natural disasters, and raids, while providing full control over the colony through trade, production chains and datas.Endzone 2
Endzone 2 is a post-apocalyptic survival colony builder, where you embark to secure humanity's survival after a cataclysmic disaster. Discover and repopulate the last habitable grounds, while the survival of your people hinges on your wits, foresight, and resilience in a harsh and unforgiving world.Land of the Vikings
Land of the Vikings is a survival colony sim game. Build and lead your village, and expand it into a thriving city. A wise Jarl must manage resources, survive harsh conditions, and guide their fellow Vikings to work together through social conflict. Skál!Autonauts vs Piratebots
Create, automate and defend an impenetrable base. Assemble and command a Bot army to combat an entire Piratebot invasion. Build, program and battle your way through five different zones.Roman Triumph: Survival City Builder
At the northern fringes of the empire, a new Roman city is born! Manage and grow your city, please the gods, and survive against barbarians and mythological threats to achieve Roman Triumph!Norland
Lead your noble family in this medieval colony sim, facing off against class conflict, religious struggle, and political treachery. Tend to your people’s needs, uncover the lost knowledge of a fallen empire, and engage in nefarious plots against your enemies.Dune: Spice Wars
A 4X real-time strategy game from the developers of the critically acclaimed Northgard. Set in Frank Herbert’s groundbreaking Dune universe, you must lead your faction and battle for control and dominance over the harsh desert planet of Arrakis.Organs Please
A dark and satirical management sim, where you take control of a recycling factory with a twist: it recycles humans. Your job is to decide who gets to escape our dying planet in a cozy spaceship and who sacrifices their blood, sweat and tears for humanity. Literally.Most played games like Big Pharma on Steam
Take a look at the top games like Big Pharma that are currently attracting the largest player bases on the Steam platform, as of April 30th 2025.
1. RimWorld
Similarity 54% A sci-fi colony sim driven by an intelligent AI storyteller. Generates stories by simulating psychology, ecology, gunplay, melee combat, climate, biomes, diplomacy, interpersonal relationships, art, medicine, trade, and more. RimWorld is a colony sim, base-building and survival game developed and published by Ludeon Studios. Released on October 17th 2018 has received 208,163 reviews of which 203,940 were positive and 4,223 were negative resulting in an impressive rating of 9.7 out of 10. The game has hit the top spot as the #1 most played game like Big Pharma, thanks to its 18,188 peak concurrent players over the last day.2. Factorio
Similarity 66% Factorio is a game about building and creating automated factories to produce items of increasing complexity, within an infinite 2D world. Use your imagination to design your factory, combine simple elements into ingenious structures, and finally protect it from the creatures who don't really like you. Factorio is a automation, base-building and resource management game developed and published by Wube Software LTD.. Released on August 14th 2020 has received 213,390 reviews of which 206,974 were positive and 6,416 were negative resulting in an impressive rating of 9.6 out of 10. While seeing 13,456 players online at once in the last 24 hours, this game is currently ranked #2 among games like Big Pharma based on player count.3. Cookie Clicker
Similarity 60% An idle game about making cookies! Originally released in 2013 on the web, and actively developed since then. This is the official version for Steam. Cookie Clicker is a clicker, idler and casual game developed by Orteil and DashNet and published by Playsaurus. Released on September 01st 2021 has received 78,685 reviews of which 76,069 were positive and 2,616 were negative resulting in an impressive rating of 9.5 out of 10. While seeing 10,734 players online at once in the last 24 hours, this game is currently ranked #3 among games like Big Pharma based on player count.4. Revolution Idle
Similarity 51% Join an experience where each revolution takes you further into the unknown! Revolution Idle challenges you to multiply your accumulators to reach unimaginable heights. Will you manage to reach infinity? Revolution Idle is a casual, simulation and idler game developed by Oni Gaming and Nu Games and published by Oni Gaming. Released on October 11th 2024 has received 3,688 reviews of which 3,140 were positive and 548 were negative resulting in a rating of 8.2 out of 10. With 8,360 concurrent players in the last 24 hours, the game currently holds the #4 spot among the most played games like Big Pharma.5. Cities: Skylines
Similarity 56% Cities: Skylines is a modern take on the classic city simulation. The game introduces new game play elements to realize the thrill and hardships of creating and maintaining a real city whilst expanding on some well-established tropes of the city building experience. Cities: Skylines is a city builder, simulation and building game developed by Colossal Order Ltd. and published by Paradox Interactive. Released on March 10th 2015 has received 274,208 reviews of which 254,907 were positive and 19,301 were negative resulting in an impressive rating of 9.2 out of 10. With 5,517 concurrent players in the last 24 hours, the game currently holds the #5 spot among the most played games like Big Pharma.6. Oxygen Not Included
Similarity 57% Oxygen Not Included is a space-colony simulation game. Deep inside an alien space rock your industrious crew will need to master science, overcome strange new lifeforms, and harness incredible space tech to survive, and possibly, thrive. Oxygen Not Included is a colony sim, base-building and survival game developed and published by Klei Entertainment. Released on July 30th 2019 has received 127,555 reviews of which 123,406 were positive and 4,149 were negative resulting in an impressive rating of 9.5 out of 10. With 4,349 concurrent players in the last 24 hours, the game currently holds the #6 spot among the most played games like Big Pharma.7. Supermarket Together
Similarity 52% The multiplayer supermarket has arrived to your neighbourhood for free! Stock your shop space, unlock perks and franchises, hire employees or chase those pesky shoplifters. The more players, the more action! Supermarket Together is a simulation, online co-op and multiplayer game developed and published by DeadDevsTellNoLies. Released on August 09th 2024 has received 64,362 reviews of which 61,131 were positive and 3,231 were negative resulting in an impressive rating of 9.3 out of 10. With 4,073 concurrent players in the last 24 hours, the game currently holds the #7 spot among the most played games like Big Pharma.8. Supermarket Simulator
Similarity 52% Run your own supermarket. Stock shelves, set prices as you'd like, take payments, hire staff, expand and design your store. Online orders & delivery, shoplifters, security, local market are upcoming. Supermarket Simulator is a simulation, management and economy game developed and published by Nokta Games. Released on February 20th 2024 has received 67,137 reviews of which 63,025 were positive and 4,112 were negative resulting in an impressive rating of 9.2 out of 10. With 2,994 concurrent players in the last 24 hours, the game currently holds the #8 spot among the most played games like Big Pharma.9. Planet Zoo
Similarity 54% Build a world for wildlife in Planet Zoo. From the developers of Planet Coaster and Zoo Tycoon comes the ultimate zoo sim. Construct detailed habitats, manage your zoo, and meet authentic living animals who think, feel and explore the world you create around them. Planet Zoo is a management, simulation and building game developed and published by Frontier Developments. Released on November 05th 2019 has received 87,057 reviews of which 79,305 were positive and 7,752 were negative resulting in a rating of 9.0 out of 10. With 2,455 concurrent players in the last 24 hours, the game currently holds the #9 spot among the most played games like Big Pharma.10. Manor Lords
Similarity 54% Manor Lords is a medieval strategy game featuring in-depth city building, large-scale tactical battles, and complex economic and social simulations. Rule your lands as a medieval lord – the seasons pass, the weather changes, and cities rise and fall. Manor Lords is a strategy, city builder and simulation game developed by Slavic Magic and published by Hooded Horse. Released on April 26th 2024 has received 70,793 reviews of which 61,238 were positive and 9,555 were negative resulting in a rating of 8.5 out of 10. With 2,051 concurrent players in the last 24 hours, the game currently holds the #10 spot among the most played games like Big Pharma.Best deals on games like Big Pharma on Steam
Discover fantastic savings with the best discounts on a variety of games like Big Pharma available on Steam right now, updated on April 30th 2025. Looking for even more deals? Use the search filters to explore a wider range of discounted games like Big Pharma.
1. Lords and Villeins
Similarity 59% Build a prosperous settlement in a unique simulation of a feudal economy - each family runs their shop, owns their goods, and trades with other villagers in a free market. You will manage the land, build houses, organise events, set taxes, and balance supply and demand while engaging in diplomacy! Lords and Villeins is a colony sim, strategy and city builder game developed by Honestly Games and published by Fulqrum Publishing. Released on November 10th 2022 has received 867 reviews of which 628 were positive and 239 were negative resulting in a rating of 7.0 out of 10. Featuring a massive 96% discount, this game currently holds the #1 spot in the best deals for games like Big Pharma.2. Naheulbeuk's Dungeon Master
Similarity 51% A dungeon in danger ! Build, manage, and defend your tower in the satirical heroic fantasy universe of Dungeon of Naheulbeuk. From a shaky establishment to an infamous lair! Naheulbeuk's Dungeon Master is a management, simulation and funny game developed by Artefacts Studio and published by Dear Villagers. Released on November 15th 2023 has received 1,391 reviews of which 998 were positive and 393 were negative resulting in a rating of 6.9 out of 10. Thanks to its incredible 96% discount, this game is now the #2 best deal in games like Big Pharma.3. Founders' Fortune
Similarity 61% A fantasy village builder focusing on creative building, colonist psychology and base defense. Handle resources, farming, production, tools, diplomacy, families, trading, defense, and research, as well as the wishes, expectations, thoughts, and equipment of every villager. Founders' Fortune is a colony sim, base-building and city builder game developed and published by Dionic Software. Released on December 18th 2020 has received 2,099 reviews of which 1,690 were positive and 409 were negative resulting in a rating of 7.8 out of 10. Thanks to its incredible 95% discount, this game is now the #3 best deal in games like Big Pharma.4. Autonauts vs Piratebots
Similarity 52% Create, automate and defend an impenetrable base. Assemble and command a Bot army to combat an entire Piratebot invasion. Build, program and battle your way through five different zones. Autonauts vs Piratebots is a simulation, strategy and automation game developed by Denki and published by Curve Games. Released on July 28th 2022 has received 480 reviews of which 380 were positive and 100 were negative resulting in a rating of 7.5 out of 10. Currently offered at a significant 95% discount, this title has earned the #4 position in the best deals for games like Big Pharma.5. Rise of Industry
Similarity 72% Put your entrepreneurial skills to the test in the first title in the ROI series as you create & optimise intricate production lines. As an early 20th-Century industrialist, grow your empire & adapt to an ever-changing business landscape with unexpected events that could lead to boom…or bust. Rise of Industry is a management, strategy and economy game developed by Dapper Penguin Studios and published by Kasedo Games. Released on May 02nd 2019 has received 4,091 reviews of which 2,996 were positive and 1,095 were negative resulting in a rating of 7.1 out of 10. Currently offered at a significant 95% discount, this title has earned the #5 position in the best deals for games like Big Pharma.6. 112 Operator
Similarity 54% Manage emergency services in any city in the world! Take calls and dispatch rescue forces. Handle difficult situations, now depending on the weather, and traffic. Help the citizens through cataclysms and natural disasters, becoming a better emergency number operator every day! 112 Operator is a simulation, realistic and casual game developed by Jutsu Games and published by Games Operators. Released on April 23rd 2020 has received 6,492 reviews of which 5,810 were positive and 682 were negative resulting in a rating of 8.7 out of 10. Currently offered at a significant 94% discount, this title has earned the #6 position in the best deals for games like Big Pharma.7. Tin Can
Similarity 51% You've barely managed to escape your exploding spaceship. Now in an old escape pod, you hurtle through space at the mercy of the cosmos. With no knowledge of the pod’s complex systems, your life depends on a technical manual and your own wits. How long can you survive? Tin Can is a simulation, space and survival game developed by Tin Can Studio and published by Tin Can Studio and IndieArk. Released on May 12th 2022 has received 1,181 reviews of which 1,000 were positive and 181 were negative resulting in a rating of 8.1 out of 10. Currently offered at a significant 94% discount, this title has earned the #7 position in the best deals for games like Big Pharma.8. Snowtopia: Ski Resort Builder
Similarity 60% Build your ideal ski resort. Keep skiers smiling with fresh pistes and fine facilities. Ski, build and chill in the wintry world of Snowtopia where everyone is welcome! Snowtopia: Ski Resort Builder is a simulation, building and management game developed by TeaForTwo and published by Goblinz Publishing and Maple Whispering Limited. Released on December 14th 2022 has received 1,169 reviews of which 717 were positive and 452 were negative resulting in a rating of 6 out of 10. Currently offered at a significant 94% discount, this title has earned the #8 position in the best deals for games like Big Pharma.9. Life is Feudal: Forest Village
Similarity 53% LiF:Forest Village is a city builder with survival aspects in a realistic harsh medieval world. Shape, build and expand your settlement, grow various food to prevent your villagers from avitaminosis and starvation. Possess them for additional micromanagement or simply to wander around. Life is Feudal: Forest Village is a city builder, colony sim and strategy game developed by Mindillusion and published by Bitbox Ltd.. Released on May 26th 2017 has received 5,881 reviews of which 3,897 were positive and 1,984 were negative resulting in a rating of 6.5 out of 10. Currently offered at a significant 93% discount, this title has earned the #9 position in the best deals for games like Big Pharma.10. Bridge Constructor Portal
Similarity 52% Enter the Aperture Science Enrichment Center and experience Bridge Constructor Portal – the unique merging of the classic Portal™ and Bridge Constructor™ games. Bridge Constructor Portal is a puzzle, simulation and strategy game developed by ClockStone and published by Headup. Released on December 20th 2017 has received 6,536 reviews of which 5,989 were positive and 547 were negative resulting in a rating of 8.9 out of 10. Currently offered at a significant 92% discount, this title has earned the #10 position in the best deals for games like Big Pharma.Free games like Big Pharma on Steam
Check out this fantastic list of free-to-play games like Big Pharma you can enjoy on Steam right now, updated on April 30th 2025. Looking for even more free titles? Use the search filters to explore a wider range of free to play games like Big Pharma.