Games like Big Pharma on Steam
For those who prefer not to search, lists of the most played, top deals and best free games like Big Pharma are available at the bottom of the page.
Most played games like Big Pharma on Steam
Take a look at the top games like Big Pharma that are currently attracting the largest player bases on the Steam platform, as of June 15th 2025.
1. Football Manager 2024
Similarity 57% Build a world-class team ready to dominate your rivals in football’s most prestigious competitions. Progress never stops when you’re pursuing footballing greatness. Football Manager 2024 is a simulation, sports and management game developed by Sports Interactive and published by SEGA. Released on November 06th 2023 has received 23,048 reviews of which 20,927 were positive and 2,121 were negative resulting in a rating of 8.9 out of 10. The game has hit the top spot as the #1 most played game like Big Pharma, thanks to its 47,542 peak concurrent players over the last day.2. Cities: Skylines
Similarity 55% Cities: Skylines is a modern take on the classic city simulation. The game introduces new game play elements to realize the thrill and hardships of creating and maintaining a real city whilst expanding on some well-established tropes of the city building experience. Cities: Skylines is a city builder, simulation and building game developed by Colossal Order Ltd. and published by Paradox Interactive. Released on March 10th 2015 has received 275,770 reviews of which 256,362 were positive and 19,408 were negative resulting in an impressive rating of 9.2 out of 10. While seeing 6,752 players online at once in the last 24 hours, this game is currently ranked #2 among games like Big Pharma based on player count.3. Captain of Industry
Similarity 55% Land your crew of survivors on an abandoned island and survive! Mine raw materials, grow food, build factories, manufacture products, research new tech, and trade with others. Become an industrial superpower! But this is no easy task, you will be put to the test to keep your settlement alive. Captain of Industry is a base-building, automation and resource management game developed and published by MaFi Games. Released on May 31st 2022 has received 7,154 reviews of which 6,737 were positive and 417 were negative resulting in an impressive rating of 9.1 out of 10. While seeing 4,520 players online at once in the last 24 hours, this game is currently ranked #3 among games like Big Pharma based on player count.4. Anno 1800
Similarity 53% Anno 1800™ – Lead the Industrial Revolution! Welcome to the dawn of the Industrial Age. The path you choose will define your world. Are you an innovator or an exploiter? A conqueror or a liberator? How the world remembers your name is up to you. Anno 1800 is a city builder, strategy and simulation game developed by Ubisoft Mainz and published by Ubisoft. Released on April 16th 2019 has received 25,091 reviews of which 20,368 were positive and 4,723 were negative resulting in a rating of 8.0 out of 10. With 3,737 concurrent players in the last 24 hours, the game currently holds the #4 spot among the most played games like Big Pharma.5. Transport Fever 2
Similarity 58% The classic transport simulation genre has a new gold standard with Transport Fever 2. Discover a whole new world by navigating transport routes through land, water and air. May progress and prosperity find their way! Transport Fever 2 is a simulation, strategy and management game developed by Urban Games and published by Good Shepherd Entertainment. Released on December 11th 2019 has received 27,627 reviews of which 24,960 were positive and 2,667 were negative resulting in a rating of 8.9 out of 10. With 2,878 concurrent players in the last 24 hours, the game currently holds the #5 spot among the most played games like Big Pharma.6. Supermarket Simulator
Similarity 52% Run your own supermarket. Stock shelves, set prices as you'd like, take payments, hire staff, expand, deal with shoplifters, and design your store. Purchase goods from online or local markets around the town. Online orders & delivery are upcoming. Supermarket Simulator is a simulation, management and economy game developed and published by Nokta Games. Released on February 20th 2024 has received 68,341 reviews of which 64,104 were positive and 4,237 were negative resulting in an impressive rating of 9.2 out of 10. With 2,677 concurrent players in the last 24 hours, the game currently holds the #6 spot among the most played games like Big Pharma.7. Jurassic World Evolution 2
Similarity 53% Jurassic World Evolution 2 is the much-anticipated sequel to Frontier’s highly successful Jurassic World Evolution. This bold new era in the Jurassic World Evolution game franchise builds upon the ground-breaking and immersive 2018 management simulation. Jurassic World Evolution 2 is a dinosaurs, building and simulation game developed and published by Frontier Developments. Released on November 09th 2021 has received 36,638 reviews of which 32,817 were positive and 3,821 were negative resulting in a rating of 8.8 out of 10. With 2,314 concurrent players in the last 24 hours, the game currently holds the #7 spot among the most played games like Big Pharma.8. shapez 2
Similarity 57% Dive into a factory-building game with the focus on just that – building huge space factories! Construct sprawling multi-level factories and satisfying production lines without limits. Tackle increasingly complex automation challenges at your own pace – you won’t have to worry about enemies. shapez 2 is a management, strategy and automation game developed by tobspr Games and published by tobspr Games and Gamirror Games. Released on August 15th 2024 has received 11,061 reviews of which 10,856 were positive and 205 were negative resulting in an impressive rating of 9.5 out of 10. With 1,872 concurrent players in the last 24 hours, the game currently holds the #8 spot among the most played games like Big Pharma.9. TCG Card Shop Simulator
Similarity 50% Open your own local game store. Stock shelves with the latest booster packs, or crack them and collect the cards for yourself. Set your own prices, hire staff, host events, and expand your card shop. TCG Card Shop Simulator is a simulation, management and economy game developed and published by OPNeon Games. Released on September 15th 2024 has received 39,499 reviews of which 38,392 were positive and 1,107 were negative resulting in an impressive rating of 9.5 out of 10. With 1,772 concurrent players in the last 24 hours, the game currently holds the #9 spot among the most played games like Big Pharma.10. Idling to Rule the Gods
Similarity 54% Idling to Rule the Gods is a free to play Idle-Game with a lot of content and some Minigames. Depending on your play-style, you can play it fast or slow. Either way it can be fun for hundreds of hours! Idling to Rule the Gods is a free to play, indie and simulation game developed and published by Shugasu GmbH. Released on May 27th 2016 has received 1,916 reviews of which 1,638 were positive and 278 were negative resulting in a rating of 8.2 out of 10. With 1,120 concurrent players in the last 24 hours, the game currently holds the #10 spot among the most played games like Big Pharma.Best deals on games like Big Pharma on Steam
Discover fantastic savings with the best discounts on a variety of games like Big Pharma available on Steam right now, updated on June 15th 2025. Looking for even more deals? Use the search filters to explore a wider range of discounted games like Big Pharma.
1. EarthX
Similarity 60% EarthX is a rocket company management game. Go from launching small rockets on Earth to eventually building a colony on Mars. Create your own Internet constellation, develop new technologies, supply the International Space Station and terraform Mars! EarthX is a simulation, indie and strategy game developed by Denis and Ry and published by Mesote Games. Released on July 12th 2023 has received 875 reviews of which 769 were positive and 106 were negative resulting in a rating of 8.3 out of 10. Featuring a massive 99% discount, this game currently holds the #1 spot in the best deals for games like Big Pharma.2. Size Matters
Similarity 48% You play as a scientist who is shrinking every second in a race against time! Find all the ingredients and formulas scattered around the laboratory, which are necessary for producing the life-saving antidote. But beware, your time is very precious. Size Matters is a simulation, casual and science game developed by Mazen Games and published by GrabTheGames. Released on March 12th 2021 has received 473 reviews of which 412 were positive and 61 were negative resulting in a rating of 8.1 out of 10. Thanks to its incredible 99% discount, this game is now the #2 best deal in games like Big Pharma.3. Railroad Corporation
Similarity 54% Relive the pioneering spirit of the Golden Age of Steam by establishing your own railroad empire across 19th century North America. Bring settlements together, produce and trade goods and develop new technologies to stay ahead of the competition. Want more? RAILROAD CORPORATION 2 Out Now! Railroad Corporation is a strategy, trains and management game developed by Corbie Games and published by Iceberg Interactive. Released on November 18th 2019 has received 1,387 reviews of which 1,028 were positive and 359 were negative resulting in a rating of 7.1 out of 10. Thanks to its incredible 99% discount, this game is now the #3 best deal in games like Big Pharma.4. Honey, I Joined a Cult
Similarity 50% It's time to start working towards that ultimate goal of enlightenment, faith and money…lots and lots of money! Become the ultimate tycoon - create, customise, and manage your own cult whilst listening to funky music. Welcome to Honey, I Joined a Cult! Honey, I Joined a Cult is a simulation, base-building and resource management game developed by Sole Survivor Games and published by Team17. Released on November 03rd 2022 has received 1,732 reviews of which 1,279 were positive and 453 were negative resulting in a rating of 7.1 out of 10. Currently offered at a significant 99% discount, this title has earned the #4 position in the best deals for games like Big Pharma.5. Autonauts vs Piratebots
Similarity 49% Create, automate and defend an impenetrable base. Assemble and command a Bot army to combat an entire Piratebot invasion. Build, program and battle your way through five different zones. Autonauts vs Piratebots is a simulation, strategy and automation game developed by Denki and published by Curve Games. Released on July 28th 2022 has received 485 reviews of which 382 were positive and 103 were negative resulting in a rating of 7.4 out of 10. Currently offered at a significant 98% discount, this title has earned the #5 position in the best deals for games like Big Pharma.6. Railroad Tycoon 3
Similarity 65% Railroad Tycoon 3 features 25 scenarios challenging players to recreate magnificent feats of railroading history from around the world. Players can lay track (including tunnels and overpasses), pick from over 40 locomotives from early steams to modern bullets, choose to haul over 35 types of cargo in a dynamic economy, and participate in... Railroad Tycoon 3 is a management, strategy and trains game developed by PopTop and published by 2K. Released on May 04th 2007 has received 1,169 reviews of which 900 were positive and 269 were negative resulting in a rating of 7.4 out of 10. Currently offered at a significant 98% discount, this title has earned the #6 position in the best deals for games like Big Pharma.7. Buzz Aldrin's Space Program Manager
Similarity 54% Space Program Manager (SPM) is the ultimate game of space exploration. It is the mid 1950s and the race for dominance between the US and the Soviet Union is about to move into a new dimension: space. Buzz Aldrin's Space Program Manager is a simulation, strategy and space game developed by Polar Motion and published by Slitherine Ltd.. Released on October 31st 2014 has received 479 reviews of which 369 were positive and 110 were negative resulting in a rating of 7.3 out of 10. Currently offered at a significant 98% discount, this title has earned the #7 position in the best deals for games like Big Pharma.8. Rise of Industry
Similarity 71% Put your entrepreneurial skills to the test in the first title in the ROI series as you create & optimise intricate production lines. As an early 20th-Century industrialist, grow your empire & adapt to an ever-changing business landscape with unexpected events that could lead to boom…or bust. Rise of Industry is a management, strategy and economy game developed by Dapper Penguin Studios and published by Kasedo Games. Released on May 02nd 2019 has received 4,100 reviews of which 3,001 were positive and 1,099 were negative resulting in a rating of 7.1 out of 10. Currently offered at a significant 98% discount, this title has earned the #8 position in the best deals for games like Big Pharma.9. Automachef
Similarity 62% Welcome to Automachef, a resource management puzzler where you design kitchens, program machinery and watch your genius come to life! It’s time to engineer tomorrow’s kitchen, today! Automachef is a simulation, indie and automation game developed by Rhombico Games and published by Team17 Digital Ltd. Released on July 23rd 2019 has received 863 reviews of which 622 were positive and 241 were negative resulting in a rating of 6.9 out of 10. Currently offered at a significant 98% discount, this title has earned the #9 position in the best deals for games like Big Pharma.10. Basement
Similarity 54% Basement is a strategy game, where you start doing illegal business to fund the development of your dream video game. It won't be easy, so get ready to deal with other gangs, cops, crazy junkies, mysterious investor and even ghosts from the past. Basement is a management, strategy and crime game developed and published by Halfbus. Released on November 10th 2019 has received 2,204 reviews of which 1,554 were positive and 650 were negative resulting in a rating of 6.9 out of 10. Currently offered at a significant 98% discount, this title has earned the #10 position in the best deals for games like Big Pharma.Free games like Big Pharma on Steam
Check out this fantastic list of free-to-play games like Big Pharma you can enjoy on Steam right now, updated on June 15th 2025. Looking for even more free titles? Use the search filters to explore a wider range of free to play games like Big Pharma.