Games like The Binding of Isaac on Steam
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NECROPOLIS: BRUTAL EDITION
NECROPOLIS: BRUTAL EDITION is a major update featuring a new playable adventurer (The Brute), a completely new outdoor environment (The Black Forest), and lots of new enemies, weapons, armor, traps, potions, scrolls, and other big improvements to the game.
Tower of Guns
Tower of Guns is a fast paced first-person-shooter for the twitch gamer... with a few randomized elements to keep it fresh with each playthrough. It's a short burst "Lunch Break FPS"... not unlike Binding of Isaac mixed with Doom 2. Tower of Guns was made by a guy named Joe (with his brother Mike composing the music).
One More Dungeon
One More Dungeon is a first person shooter roguelike with procedurally generated levels and pixel-art graphics.
Has-Been Heroes
Has-Been Heroes is a challenging, lane-based roguelike game of strategy and action, featuring a band of heroes on a quest to escort the King's twin princesses to school!
One Step From Eden
Build a powerful deck, cast spells on the fly, battle evolving enemies, find game-changing artifacts, make friends or make enemies, just make it to Eden.
Catacomb Kids
Catacomb Kids is a brutal platformer roguelike that pits you against the deadly Catacombs aided only by magic, steel, and your quick reflexes. Traverse procedurally generated dungeons and hack, slash, burn, and blast your way through hordes of things that want to kill you.
GALAK-Z
Brand New features!! The Void DLC offers endless gameplay, Online Leaderboards, and a Daily Challenge that allows players to compete worldwide for the top score. Anime inspired 2D space combat simulation at its best! GALAK-Z is a modern, A.I.
Rencounter
Rencounter is a difficult, turn-based, RPG, roguelike game with a mysterious atmosphere. Help your squad survive while navigating through a network of tunnels and rooms. Distribute provisions and medicine to keep them alive.
RICO
Two cops, one case and only 24 hours to bust the bad guys! Become a loose cannon police detective and face off with criminal gangs in this procedurally-generated action movie FPS. Join forces with a friend and take down those crooks, buddy-cop style!
Dead Estate
Cornered with nowhere else to turn, can you escape the monster-filled mansion? Dead Estate is a gory, fast-paced, challenging roguelike shooter with a heavy emphasis on horror.
SYNTHETIK: Legion Rising
SYNTHETIK is an unforgiving tactical shooter rogue-lite where freedom and experimentation is key. Fight in a world overrun by the Machine Legion and their Gods. Experience the next level in gun-play and dive into unparalleled build options and Android upgrades. Can you defeat the Heart of Armageddon?
bit Dungeon II
bitDungeon II is fast action-adventure game with a giant overworld to explore. You are a spirit in an undead world of demons. Your "loved one's " grave has been desecrated. Fight through these corrupted lands, and bring peace to her soul.
CRYPTARK
Cryptark is a 2D sci-fi shooter where you take on the role of a heavily armed privateer seeking to earn government contracts by boarding deadly alien space-hulks. It's up to you to strategize a plan of attack, pick an equipment loadout, and destroy the central core to be victorious.
FTL: Faster Than Light
This "spaceship simulation roguelike-like" allows you to take your ship and crew on an adventure through a randomly generated galaxy filled with glory and bitter defeat.
Space Gladiators
Ever dreamt of being a space potato? Now’s your chance! Space Gladiators is a 2D hand-drawn roguelite platformer following a bunch of captives fighting their way out of a planet prison. Defeat hordes of aliens in the gladiatorial arenas and earn your freedom!
Switchcars
Escape alien beasts across varying environments and eras, in more than 1300 unique vehicles! Add your own vehicles and props with the included editor.
Flamebreak
Flamebreak is a roguelite action RPG featuring a unique blend of twinstick meets MOBA arena combat. Each procedurally generated run presents new challenges while your randomized hero's race, weapon, and skills inspire new playstyles and character builds.
Beat Blast
Create musical beats that kill. Beat Blast is a music maker, bullet hell, dungeon crawler, roguelite. Battle through dungeons and defeat big bosses. Collect weapons, passives and musical instruments!
Kelipot
A mysterious plague befell ancient Celephais. What choices await the twins lost in the chaos? The Roguelite action-platformer Kelipot is here! With a rich story experience, frame-by-frame animations and hand-illustrated 2D visuals. Explore and uncover the truth beneath this twisted world!
Lost in Random: The Eternal Die
Hack and slash your way to freedom from an eternal prison in this roguelike dungeon crawler where every run is unique. Earn relics and align them cleverly for devastating builds. Wield your living die-companion as a weapon of chaos and fight your way through the warped world of the black die.
Heart&Slash
Fight as Heart, an innocent robot fighting to escape the grip of mindless machines in a future where humans are no more. A fast-paced 3D brawler with roguelike elements set in a colorful yet desolated world.
Space Beast Terror Fright
S.B.T.F. is a very hard arcade-style / rogue-like / perma-death first person shooter. You play as Marines who must brave dark, claustrophobic and terrifyingly intense Space Beast infested spacecraft in order to extract critical data and lucrative upgrades. Can you make it out alive?
Twilight Survivors
A time-limited survival game infused with rogue-lite elements and an adorable art style! The world has plunged into darkness, and you are its sole beacon of hope. Will you endure until dawn, or succumb to repeated deaths in your quest? Fear not, for you can collect more coins to arm yourself!