Best Medical Sim Games on Steam
Unlike generic lists, our strategy game recommendations use a rigorous analysis of Steam user reviews to identify and feature only the best, community-validated medical sim games. For those who prefer not to search, lists of the most played, top deals and best free medical sim games are available at the bottom of the page.
Most played medical sim games on Steam
Take a look at the top medical sim games that are currently attracting the largest player bases on the Steam platform, as of June 14th 2025.
1. Two Point Hospital
Design stunning hospitals, cure peculiar illnesses and manage troublesome staff as you spread your budding healthcare organisation across Two Point County. Two Point Hospital is a simulation, management and medical sim game developed by Two Point Studios and published by SEGA. Released on August 29th 2018 has received 33,274 reviews of which 30,563 were positive and 2,711 were negative resulting in an impressive rating of 9 out of 10. The game has hit the top spot as the #1 most played medical sim game, thanks to its 397 peak concurrent players over the last day.2. Project Hospital
Become an ace doctor, an aspiring architect and a successful manager at the same time. Design your very own hospital, tweak every detail or choose one of the prebuilt scenarios and just jump to the doctor’s duty. Project Hospital is a medical sim, city builder and management game developed and published by Oxymoron Games. Released on October 30th 2018 has received 8,348 reviews of which 7,392 were positive and 956 were negative resulting in a rating of 8.6 out of 10. While seeing 336 players online at once in the last 24 hours, this game is currently ranked #2 among medical sim games based on player count.3. Do No Harm
Lovecraftian Doctor Simulator. Diagnose patients by analyzing unsettling symptoms and treat them using your Book of Medicine. Make moral choices — decide who to save or kill, discover whom to trust, and unlock multiple endings! Can you endure 30 days of perilous decisions? Do No Harm is a lovecraftian, medical sim and story rich game developed by Darts Games and published by Darts Games and Hawthorn Games. Released on March 06th 2025 has received 599 reviews of which 443 were positive and 156 were negative resulting in a rating of 7.1 out of 10. The game currently holds the #3 spot among the most played medical sim games.4. Bio Inc. Redemption
Bio Inc.: Redemption is a realistic simulation and strategy game in which you make life or death decisions. Create a deadly illness to infect and torment your victim or play as the head of a medical team and hopefully find a cure to save your human patient. Will you be the plague or preserve humanity? Bio Inc. Redemption is a medical sim, outbreak sim and simulation game developed and published by DryGin Studios. Released on March 08th 2018 has received 2,307 reviews of which 2,058 were positive and 249 were negative resulting in a rating of 8.5 out of 10. The game currently holds the #4 spot among the most played medical sim games.5. Surgeon Simulator
Surgeon Simulator is an over-the-top operation sim, stitching together pitch-black humour with life-saving surgery. Become Dr. Burke, a would-be surgeon with a less than conventional toolkit, as he performs procedures on patients including the Heavy from TF2! ...is that a hammer? Surgeon Simulator is a simulation, funny and physics game developed by Bossa Studios and published by Infogrames. Released on April 19th 2013 has received 16,493 reviews of which 13,566 were positive and 2,927 were negative resulting in a rating of 8.1 out of 10. The game currently holds the #5 spot among the most played medical sim games.6. Weedcraft Inc
Weedcraft Inc explores the business of producing, breeding and selling weed in America, delving deep into the financial, political and cultural aspects of the country's complex relationship with this troublesome and promising plant. Weedcraft Inc is a simulation, strategy and indie game developed by Vile Monarch and published by Devolver Digital. Released on April 11th 2019 has received 1,632 reviews of which 1,311 were positive and 321 were negative resulting in a rating of 7.7 out of 10. The game currently holds the #6 spot among the most played medical sim games.7. Big Pharma
What if you had it in your power to rid the world of disease, to improve the lives of millions, to ease suffering and cure the sick… and earn a tidy profit? As the head of your own Pharmaceutical Conglomerate you have this power resting in your hands. Will you use it for good? Big Pharma is a management, simulation and medical sim game developed by Twice Circled and published by Positech Games. Released on August 27th 2015 has received 1,883 reviews of which 1,458 were positive and 425 were negative resulting in a rating of 7.5 out of 10. The game currently holds the #7 spot among the most played medical sim games.8. Night Shift Nurses
A washed-up mad doctor is hired back by a devious former test subject and asked to twist her hospital into a corrupt donation mill. Will he seize this second chance to practice his own vision of "science," or will his many failings drag him down once again in this pseudo-medical visual novel? Night Shift Nurses is a romance, visual novel and 1990's game developed and published by Shiravune. Released on December 16th 2024 has received 438 reviews of which 376 were positive and 62 were negative resulting in a rating of 8.0 out of 10. The game currently holds the #8 spot among the most played medical sim games.9. Galacticare
Build, manage and optimise intergalactic hospitals! Recruit staff to satisfy the whims of various alien species, and cure their bizarre illnesses - for money! Save the (literal) Galaxy in story mode, or head into sandbox to design the hospital of your dreams. Galacticare is a story rich, casual and medical sim game developed by Brightrock Games and published by Mythwright. Released on May 23rd 2024 has received 570 reviews of which 503 were positive and 67 were negative resulting in a rating of 8.3 out of 10. The game currently holds the #9 spot among the most played medical sim games.10. Accident
Become a journalist who researches old car accident cases. Help victims and perform first aid, obtain evidence and reconstruct the events to discover what really happened. Accident is a simulation, casual and medical sim game developed by Duality Games and Glob Games Studio and published by Duality Games, PlayWay S.A. and HeartBeat Games. Released on September 21st 2021 has received 1,547 reviews of which 1,197 were positive and 350 were negative resulting in a rating of 7.4 out of 10. The game currently holds the #10 spot among the most played medical sim games.Best deals on medical sim games on Steam
Discover fantastic savings with the best discounts on a variety of medical sim games available on Steam right now, updated on June 14th 2025. Looking for even more deals? Use the search filters to explore a wider range of discounted medical sim games.
1. Accident
Become a journalist who researches old car accident cases. Help victims and perform first aid, obtain evidence and reconstruct the events to discover what really happened. Accident is a simulation, casual and medical sim game developed by Duality Games and Glob Games Studio and published by Duality Games, PlayWay S.A. and HeartBeat Games. Released on September 21st 2021 has received 1,547 reviews of which 1,197 were positive and 350 were negative resulting in a rating of 7.4 out of 10. Featuring a massive 92% discount, this game currently holds the #1 spot in the best deals for medical sim category.2. Weedcraft Inc
Weedcraft Inc explores the business of producing, breeding and selling weed in America, delving deep into the financial, political and cultural aspects of the country's complex relationship with this troublesome and promising plant. Weedcraft Inc is a simulation, strategy and indie game developed by Vile Monarch and published by Devolver Digital. Released on April 11th 2019 has received 1,632 reviews of which 1,311 were positive and 321 were negative resulting in a rating of 7.7 out of 10. Thanks to its incredible 88% discount, this game is now the #2 best deal in medical sim games.3. Project Hospital
Become an ace doctor, an aspiring architect and a successful manager at the same time. Design your very own hospital, tweak every detail or choose one of the prebuilt scenarios and just jump to the doctor’s duty. Project Hospital is a medical sim, city builder and management game developed and published by Oxymoron Games. Released on October 30th 2018 has received 8,348 reviews of which 7,392 were positive and 956 were negative resulting in a rating of 8.6 out of 10. Thanks to its incredible 61% discount, this game is now the #3 best deal in medical sim games.4. Big Pharma
What if you had it in your power to rid the world of disease, to improve the lives of millions, to ease suffering and cure the sick… and earn a tidy profit? As the head of your own Pharmaceutical Conglomerate you have this power resting in your hands. Will you use it for good? Big Pharma is a management, simulation and medical sim game developed by Twice Circled and published by Positech Games. Released on August 27th 2015 has received 1,883 reviews of which 1,458 were positive and 425 were negative resulting in a rating of 7.5 out of 10. Currently offered at a 49% discount, this title has earned the #4 position in the best deals for medical sim games.5. Two Point Hospital
Design stunning hospitals, cure peculiar illnesses and manage troublesome staff as you spread your budding healthcare organisation across Two Point County. Two Point Hospital is a simulation, management and medical sim game developed by Two Point Studios and published by SEGA. Released on August 29th 2018 has received 33,274 reviews of which 30,563 were positive and 2,711 were negative resulting in an impressive rating of 9 out of 10. Currently offered at a 37% discount, this title has earned the #5 position in the best deals for medical sim games.6. Night Shift Nurses
A washed-up mad doctor is hired back by a devious former test subject and asked to twist her hospital into a corrupt donation mill. Will he seize this second chance to practice his own vision of "science," or will his many failings drag him down once again in this pseudo-medical visual novel? Night Shift Nurses is a romance, visual novel and 1990's game developed and published by Shiravune. Released on December 16th 2024 has received 438 reviews of which 376 were positive and 62 were negative resulting in a rating of 8.0 out of 10. Currently offered at a 20% discount, this title has earned the #6 position in the best deals for medical sim games.Free medical sim games on Steam
Check out this fantastic list of free-to-play medical sim games you can enjoy on Steam right now, updated on June 14th 2025. Looking for even more free titles? Use the search filters to explore a wider range of free to play medical sim games.